de-, 向下，离开。part, 分开，部分。即离开，分开。

depart

depart: [13] Depart originally meant ‘divide’. This was the sense of its ultimate Latin ancestor dispertīre, literally ‘separate up into constituent parts’, a compound verb formed from the prefix dis-, denoting separation, and partīre ‘divide, distribute’, a derivative of the noun pars ‘part’. It passed into English via Vulgar Latin *dēpartīre and Old French departir, by which time the notions of ‘division’ and ‘separation’ had already produced the intransitive sense ‘go away’.
=> part

depart (v.)

mid-13c., "part from each other," from Old French departir (10c.) "to divide, distribute; separate (oneself), depart; die," from Late Latin departire "divide" (transitive), from de- "from" (see de-) + partire "to part, divide," from pars (genitive partis) "a part" (see part (n.)).

As a euphemism for "to die" (to depart this life; compare Old French departir de cest siecle) it is attested from c. 1500, as is the departed for "the dead," singly or collectively. Transitive lingers in some English usages; the wedding service was till death us depart until 1662. Related: Departed; departing.

1. My connecting plane didn't depart for another six hours.

我搭乘的联运航班又过了6个小时才起飞。

来自柯林斯例句

2. Lipton is planning to depart from the company he founded.

利普顿打算离开他创立的那家公司。

来自柯林斯例句

3. We do depart for Wales on the morrow.

我们明天确实要前往威尔士。

来自柯林斯例句

4. Flights for Rome depart from Terminal 3.

飞往罗马的班机从3号航站楼出发。

来自《权威词典》

5. We must needs depart.

我们必须离开。

来自《权威词典》